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Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis

Retinoic acid (RA) is required for pancreas specification in Xenopus and other vertebrates. However, the gene network that is directly induced by RA signalling in this context remains to be defined. By RNA sequencing of in vitro-generated pancreatic explants, we identified the genes encoding the tra...

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Detalles Bibliográficos
Autores principales: Gere-Becker, Maja B., Pommerenke, Claudia, Lingner, Thomas, Pieler, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031401/
https://www.ncbi.nlm.nih.gov/pubmed/29769220
http://dx.doi.org/10.1242/dev.161372