Cargando…

A twist defect mechanism for ATP-dependent translocation of nucleosomal DNA

As superfamily 2 (SF2)-type translocases, chromatin remodelers are expected to use an inchworm-type mechanism to walk along DNA. Yet how they move DNA around the histone core has not been clear. Here we show that a remodeler ATPase motor can shift large segments of DNA by changing the twist and leng...

Descripción completa

Detalles Bibliográficos
Autores principales: Winger, Jessica, Nodelman, Ilana M, Levendosky, Robert F, Bowman, Gregory D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031429/
https://www.ncbi.nlm.nih.gov/pubmed/29809147
http://dx.doi.org/10.7554/eLife.34100