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A twist defect mechanism for ATP-dependent translocation of nucleosomal DNA
As superfamily 2 (SF2)-type translocases, chromatin remodelers are expected to use an inchworm-type mechanism to walk along DNA. Yet how they move DNA around the histone core has not been clear. Here we show that a remodeler ATPase motor can shift large segments of DNA by changing the twist and leng...
Autores principales: | Winger, Jessica, Nodelman, Ilana M, Levendosky, Robert F, Bowman, Gregory D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031429/ https://www.ncbi.nlm.nih.gov/pubmed/29809147 http://dx.doi.org/10.7554/eLife.34100 |
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