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An Alternative Macrophage Activation Pathway Regulator, CHIT1, May Provide a Serum and Synovial Fluid Biomarker of Periprosthetic Osteolysis

BACKGROUND: Periprosthetic osteolysis (PPO) is a frequent indication for total hip replacement (THR) failure. Currently, PPO diagnosis occurs in advanced stages that often necessitate complex revisions due to bone loss. PPO biomarkers could facilitate earlier diagnosis. Alternative macrophage activa...

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Detalles Bibliográficos
Autores principales: Trehan, Samir K., Zambrana, Lester, Jo, Jonathan E., Purdue, Ed, Karamitros, Athanos, Nguyen, Joseph T., Lane, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031547/
https://www.ncbi.nlm.nih.gov/pubmed/29983656
http://dx.doi.org/10.1007/s11420-017-9598-9