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Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

CarD is an essential global transcription regulator from Mycobacterium tuberculosis (Mtb) that binds RNA polymerase and activates transcription by stabilizing the transcription initiation complex. Available crystal structures have captured two distinct, monomeric and domain-swapped homodimeric, olig...

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Detalles Bibliográficos
Autores principales: Kaur, Gundeep, Kaundal, Soni, Kapoor, Srajan, Grimes, Jonathan M., Huiskonen, Juha T., Thakur, Krishan Gopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031611/
https://www.ncbi.nlm.nih.gov/pubmed/29973616
http://dx.doi.org/10.1038/s41598-018-28290-4