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MicroRNA expression analysis identifies a subset of downregulated miRNAs in ALS motor neuron progenitors

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder that is characterized by a progressive degeneration of motor neurons (MNs). The pathomechanism underlying the disease is largely unknown, even though increasing evidence suggests that RNA metabolism, including microRNAs (miRNAs) ma...

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Detalles Bibliográficos
Autores principales: Rizzuti, Mafalda, Filosa, Giuseppe, Melzi, Valentina, Calandriello, Luca, Dioni, Laura, Bollati, Valentina, Bresolin, Nereo, Comi, Giacomo Pietro, Barabino, Silvia, Nizzardo, Monica, Corti, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031650/
https://www.ncbi.nlm.nih.gov/pubmed/29973608
http://dx.doi.org/10.1038/s41598-018-28366-1