Peptide density targets and impedes triple negative breast cancer metastasis

The C-X-C chemokine receptor type 4 (CXCR4, CD184) pathway is a key regulator of cancer metastasis. Existing therapeutics that block CXCR4 signaling are dependent on single molecule-receptor interactions or silencing CXCR4 expression. CXCR4 localizes in lipid rafts and forms dimers therefore CXCR4 t...

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Detalles Bibliográficos
Autores principales: Liu, Daxing, Guo, Peng, McCarthy, Craig, Wang, Biran, Tao, Yu, Auguste, Debra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031661/
https://www.ncbi.nlm.nih.gov/pubmed/29973594
http://dx.doi.org/10.1038/s41467-018-05035-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031661/
https://www.ncbi.nlm.nih.gov/pubmed/29973594
http://dx.doi.org/10.1038/s41467-018-05035-5

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