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Direct evidence of a low barrier hydrogen bond in the catalytic triad of a Serine protease
Serine proteases are one of the largest groups of enzymes, found in both eukaryotes and prokaryotes, and are responsible for many different functions. The detailed information about the hydrogen-bonds in the catalytic triad (Asp…His…Ser) of these enzymes is of importance in order to fully understand...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031666/ https://www.ncbi.nlm.nih.gov/pubmed/29973622 http://dx.doi.org/10.1038/s41598-018-28441-7 |