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Direct evidence of a low barrier hydrogen bond in the catalytic triad of a Serine protease

Serine proteases are one of the largest groups of enzymes, found in both eukaryotes and prokaryotes, and are responsible for many different functions. The detailed information about the hydrogen-bonds in the catalytic triad (Asp…His…Ser) of these enzymes is of importance in order to fully understand...

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Detalles Bibliográficos
Autores principales: Agback, Peter, Agback, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031666/
https://www.ncbi.nlm.nih.gov/pubmed/29973622
http://dx.doi.org/10.1038/s41598-018-28441-7