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Arguing for Adaptive Clinical Trials in Sepsis

Sepsis is life-threatening organ dysfunction due to dysregulated response to infection. Patients with sepsis exhibit wide heterogeneity stemming from genetic, molecular, and clinical factors as well as differences in pathogens, creating challenges for the development of effective treatments. Several...

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Detalles Bibliográficos
Autores principales: Talisa, Victor B., Yende, Sachin, Seymour, Christopher W., Angus, Derek C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031704/
https://www.ncbi.nlm.nih.gov/pubmed/30002660
http://dx.doi.org/10.3389/fimmu.2018.01502