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Adding a C-terminal Cysteine (CTC) Can Enhance the Bactericidal Activity of Three Different Antimicrobial Peptides

The emergence of antibiotic-resistant bacteria has threatened our health worldwide. There is an urgent need for novel antibiotics. Previously, we identified a novel 37-mer antimicrobial peptide (AMP), HBcARD, with broad spectrum antimicrobial activity. Here, we improved the efficacy of HBcARD, by re...

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Detalles Bibliográficos
Autores principales: Chen, Heng-Li, Su, Pei-Yi, Kuo, Shu-Chen, Lauderdale, Tsai-Ling Y., Shih, Chiaho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031733/
https://www.ncbi.nlm.nih.gov/pubmed/30002652
http://dx.doi.org/10.3389/fmicb.2018.01440