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Vectorized Delivery of Alpha-GalactosylCeramide and Tumor Antigen on Filamentous Bacteriophage fd Induces Protective Immunity by Enhancing Tumor-Specific T Cell Response

We have exploited the properties of filamentous bacteriophage fd to deliver immunologically active lipids together with antigenic peptides. Filamentous bacteriophages resemble for size, capability to be permeable to blood vessels, and high density antigen expression, a nature-made nanoparticle. In a...

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Detalles Bibliográficos
Autores principales: Sartorius, Rossella, D’Apice, Luciana, Barba, Pasquale, Cipria, Deborah, Grauso, Laura, Cutignano, Adele, De Berardinis, Piergiuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031736/
https://www.ncbi.nlm.nih.gov/pubmed/30002659
http://dx.doi.org/10.3389/fimmu.2018.01496