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Cyclic Stretch Negatively Regulates IL-1β Secretion Through the Inhibition of NLRP3 Inflammasome Activation by Attenuating the AMP Kinase Pathway

Macrophages are immune cells of hematopoietic origin that play diverse roles in host defenses and tissue homeostasis. In mechanical microenvironments, macrophages receive mechanical signals that regulate various cellular functions. However, the mechanisms by which mechanical signals influence the ph...

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Detalles Bibliográficos
Autores principales: Maruyama, Kentaro, Sakisaka, Yukihiko, Suto, Mizuki, Tada, Hiroyuki, Nakamura, Takashi, Yamada, Satoru, Nemoto, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031751/
https://www.ncbi.nlm.nih.gov/pubmed/30002631
http://dx.doi.org/10.3389/fphys.2018.00802