Inhibition of protein arginine methyltransferase 3 activity selectively impairs liver X receptor‐driven transcription of hepatic lipogenic genes in vivo

BACKGROUND AND PURPOSE: Agonists for the liver X receptor (LXR) are considered promising therapeutic moieties in cholesterol‐driven diseases by promoting cellular cholesterol efflux pathways. However, current clinical application of these agents is hampered by concomitant LXR‐induced activation of a...

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Detalles Bibliográficos
Autores principales: Nahon, Joya E, Groeneveldt, Christianne, Geerling, Janine J, van Eck, Miranda, Hoekstra, Menno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031883/
https://www.ncbi.nlm.nih.gov/pubmed/29774529
http://dx.doi.org/10.1111/bph.14361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031883/
https://www.ncbi.nlm.nih.gov/pubmed/29774529
http://dx.doi.org/10.1111/bph.14361

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