Asiatic Acid Prevents Oxidative Stress and Apoptosis by Inhibiting the Translocation of α-Synuclein Into Mitochondria

The association of α-synuclein (α-syn) with mitochondria occurs through interaction with mitochondrial complex I. Defects in this protein have been linked to the pathogenesis of Parkinson disease (PD). Overexpression of α-synuclein in cells has been suggested to cause elevations in mitochondrial oxi...

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Detalles Bibliográficos
Autores principales: Ding, Hongqun, Xiong, Yuyun, Sun, Jing, Chen, Chen, Gao, Jing, Xu, Huaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031891/
https://www.ncbi.nlm.nih.gov/pubmed/30002614
http://dx.doi.org/10.3389/fnins.2018.00431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031891/
https://www.ncbi.nlm.nih.gov/pubmed/30002614
http://dx.doi.org/10.3389/fnins.2018.00431

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