Cargando…
Asiatic Acid Prevents Oxidative Stress and Apoptosis by Inhibiting the Translocation of α-Synuclein Into Mitochondria
The association of α-synuclein (α-syn) with mitochondria occurs through interaction with mitochondrial complex I. Defects in this protein have been linked to the pathogenesis of Parkinson disease (PD). Overexpression of α-synuclein in cells has been suggested to cause elevations in mitochondrial oxi...
Autores principales: | Ding, Hongqun, Xiong, Yuyun, Sun, Jing, Chen, Chen, Gao, Jing, Xu, Huaxi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031891/ https://www.ncbi.nlm.nih.gov/pubmed/30002614 http://dx.doi.org/10.3389/fnins.2018.00431 |
Ejemplares similares
-
Asiatic Acid Prevents Retinal Ganglion Cell Apoptosis in a Rat Model of Glaucoma
por: Huang, Wanjing, et al.
Publicado: (2018) -
Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress
por: Menges, Stefanie, et al.
Publicado: (2017) -
The Close Encounter Between Alpha-Synuclein and Mitochondria
por: Vicario, Mattia, et al.
Publicado: (2018) -
Mitochondria-Dependent Apoptosis of Con A-Activated T Lymphocytes Induced by Asiatic Acid for Preventing Murine Fulminant Hepatitis
por: Guo, Wenjie, et al.
Publicado: (2012) -
Asiatic acid inhibits lung cancer cell growth in vitro and in vivo by destroying mitochondria
por: Wu, Tiancong, et al.
Publicado: (2017)