Cx43 Channel Gating and Permeation: Multiple Phosphorylation-Dependent Roles of the Carboxyl Terminus

Connexin 43 (Cx43), a gap junction protein seemingly fit to support cardiac impulse propagation and synchronic contraction, is phosphorylated in normoxia by casein kinase 1 (CK1). However, during cardiac ischemia or pressure overload hypertrophy, this phosphorylation fades, Cx43 abundance decreases...

Descripción completa

Detalles Bibliográficos
Autores principales: Ek-Vitorín, José F., Pontifex, Tasha K., Burt, Janis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032060/
https://www.ncbi.nlm.nih.gov/pubmed/29867029
http://dx.doi.org/10.3390/ijms19061659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032060/
https://www.ncbi.nlm.nih.gov/pubmed/29867029
http://dx.doi.org/10.3390/ijms19061659

Ejemplares similares