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Cx43 Channel Gating and Permeation: Multiple Phosphorylation-Dependent Roles of the Carboxyl Terminus

Connexin 43 (Cx43), a gap junction protein seemingly fit to support cardiac impulse propagation and synchronic contraction, is phosphorylated in normoxia by casein kinase 1 (CK1). However, during cardiac ischemia or pressure overload hypertrophy, this phosphorylation fades, Cx43 abundance decreases...

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Detalles Bibliográficos
Autores principales:	Ek-Vitorín, José F., Pontifex, Tasha K., Burt, Janis M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032060/ https://www.ncbi.nlm.nih.gov/pubmed/29867029 http://dx.doi.org/10.3390/ijms19061659

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