Isobavachalcone from Angelica keiskei Inhibits Adipogenesis and Prevents Lipid Accumulation

We isolated isobavachalcone (IBC) from Angelica keiskei (AK) as an anti-obesity component. IBC dose-dependently inhibited 3T3-L1 adipocyte differentiation by down-regulating adipogenic factors. At the mitotic clonal expansion stage (MCE), IBC caused cell cycle arrest in G0/G1 with decreased expressi...

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Detalles Bibliográficos
Autores principales: Lee, Hyejin, Li, Hua, Kweon, Minson, Choi, Youngsook, Kim, Min Jung, Ryu, Jae-Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032101/
https://www.ncbi.nlm.nih.gov/pubmed/29882838
http://dx.doi.org/10.3390/ijms19061693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032101/
https://www.ncbi.nlm.nih.gov/pubmed/29882838
http://dx.doi.org/10.3390/ijms19061693

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