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Sirt1 Protects against Oxidative Stress-Induced Apoptosis in Fibroblasts from Psoriatic Patients: A New Insight into the Pathogenetic Mechanisms of Psoriasis

Psoriasis, a multisystem chronic disease characterized by abnormal keratinocyte proliferation, has an unclear pathogenesis where systemic inflammation and oxidative stress play mutual roles. Dermal fibroblasts, which are known to provide a crucial microenvironment for epidermal keratinocyte function...

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Detalles Bibliográficos
Autores principales: Becatti, Matteo, Barygina, Victoria, Mannucci, Amanda, Emmi, Giacomo, Prisco, Domenico, Lotti, Torello, Fiorillo, Claudia, Taddei, Niccolò
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032104/
https://www.ncbi.nlm.nih.gov/pubmed/29799444
http://dx.doi.org/10.3390/ijms19061572