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Effects of PTEN Loss and Activated KRAS Overexpression on Mechanical Properties of Breast Epithelial Cells

It has previously been shown that the simultaneous activation of PI3K (phosphatidylinositol 3-kinase) and Ras/MAPK (mitogen-activated protein kinases) pathways facilitate tumor growth despite only inducing cancer cell dormancy individually. Determining the impacts on cellular mechanics each pathway...

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Detalles Bibliográficos
Autores principales: Linthicum, Will, Thanh, Minh-Tri Ho, Vitolo, Michele I., Wen, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032141/
https://www.ncbi.nlm.nih.gov/pubmed/29848992
http://dx.doi.org/10.3390/ijms19061613