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Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen

Monoterpenes R-pulegone (PUL) and R-menthofuran (MF), abundant in the Lamiaceae family, are frequently used in herb and food products. Although their hepatotoxicity was shown in rodent species, information about their effects in human liver has been limited. The aim of our study was to test the effe...

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Detalles Bibliográficos
Autores principales: Zárybnický, Tomáš, Matoušková, Petra, Lancošová, Bibiána, Šubrt, Zdeněk, Skálová, Lenka, Boušová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032148/
https://www.ncbi.nlm.nih.gov/pubmed/29921785
http://dx.doi.org/10.3390/ijms19061805