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Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen
Monoterpenes R-pulegone (PUL) and R-menthofuran (MF), abundant in the Lamiaceae family, are frequently used in herb and food products. Although their hepatotoxicity was shown in rodent species, information about their effects in human liver has been limited. The aim of our study was to test the effe...
Autores principales: | Zárybnický, Tomáš, Matoušková, Petra, Lancošová, Bibiána, Šubrt, Zdeněk, Skálová, Lenka, Boušová, Iva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032148/ https://www.ncbi.nlm.nih.gov/pubmed/29921785 http://dx.doi.org/10.3390/ijms19061805 |
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