Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2

Doxorubicin (DOX) is a widely used antineoplastic agent in clinics. However, its clinical application is largely limited by its cardiotoxicity. Diethyl blechnic (DB) is a novel compound isolated from Salvia miltiorrhiza Bunge. Here, we study the effect of DB on DOX-induced cardiotoxicity and its und...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jie, Gao, Hongwei, Wu, Chuanhong, Xu, Qiong-Ming, Lu, Jin-Jian, Chen, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032151/
https://www.ncbi.nlm.nih.gov/pubmed/29921821
http://dx.doi.org/10.3390/ijms19061809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032151/
https://www.ncbi.nlm.nih.gov/pubmed/29921821
http://dx.doi.org/10.3390/ijms19061809

Ejemplares similares