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Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2
Doxorubicin (DOX) is a widely used antineoplastic agent in clinics. However, its clinical application is largely limited by its cardiotoxicity. Diethyl blechnic (DB) is a novel compound isolated from Salvia miltiorrhiza Bunge. Here, we study the effect of DB on DOX-induced cardiotoxicity and its und...
Autores principales: | Yu, Jie, Gao, Hongwei, Wu, Chuanhong, Xu, Qiong-Ming, Lu, Jin-Jian, Chen, Xiuping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032151/ https://www.ncbi.nlm.nih.gov/pubmed/29921821 http://dx.doi.org/10.3390/ijms19061809 |
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