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Caveolin-1 Scaffolding Domain Peptides Alleviate Liver Fibrosis by Inhibiting TGF-β1/Smad Signaling in Mice

Liver fibrosis is the common pathological process characterized by activation of hepatic stellate cells (HSCs) and overproduction of extracellular matrix (ECM). Caveolin-1 (Cav1), the principal component of caveolae, is regarded as an important inhibitor of multiple signaling molecules including tra...

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Detalles Bibliográficos
Autores principales: Lu, Jing, Zhang, Jie, Wang, Yan, Sun, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032240/
https://www.ncbi.nlm.nih.gov/pubmed/29891777
http://dx.doi.org/10.3390/ijms19061729