Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction

The pregnane X receptor (PXR) is a drug/xenobiotic-activated transcription factor of crucial importance for major cytochrome P450 xenobiotic-metabolizing enzymes (CYP) expression and regulation in the liver and the intestine. One of the major target genes regulated by PXR is the cytochrome P450 enzy...

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Detalles Bibliográficos
Autores principales: Duintjer Tebbens, Jurjen, Azar, Malek, Friedmann, Elfriede, Lanzendörfer, Martin, Pávek, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032247/
https://www.ncbi.nlm.nih.gov/pubmed/29914136
http://dx.doi.org/10.3390/ijms19061785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032247/
https://www.ncbi.nlm.nih.gov/pubmed/29914136
http://dx.doi.org/10.3390/ijms19061785

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