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Insulin-Like Growth Factor-1 as a Possible Alternative to Bone Morphogenetic Protein-7 to Induce Osteogenic Differentiation of Human Mesenchymal Stem Cells in Vitro

Growth factors and mesenchymal stem cells (MSC) support consolidation of bone defects. Bone Morphogenetic Protein-7 (BMP-7) has been used clinically and experimentally, but the outcomes remain controversial. Increased systemic expression of Insulin-like Growth Factor-1 (IGF-1) significantly correlat...

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Detalles Bibliográficos
Autores principales: Reible, Bruno, Schmidmaier, Gerhard, Moghaddam, Arash, Westhauser, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032281/
https://www.ncbi.nlm.nih.gov/pubmed/29874864
http://dx.doi.org/10.3390/ijms19061674