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Methyl 3,4-Dihydroxybenzoate Enhances Resistance to Oxidative Stressors and Lifespan in C. elegans Partially via daf-2/daf-16

Genetic studies have elucidated mechanisms that regulate aging; however, there has been little progress in identifying drugs that retard ageing. Caenorhabditis elegans is among the classical model organisms in ageing research. Methyl 3,4-dihydroxybenzoate (MDHB) can prolong the life-span of C. elega...

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Detalles Bibliográficos
Autores principales: Mi, Xiang-Nan, Wang, Li-Fang, Hu, Yang, Pan, Jun-Ping, Xin, Yi-Rong, Wang, Jia-Hui, Geng, Hai-Ju, Hu, Song-Hui, Gao, Qin, Luo, Huan-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032309/
https://www.ncbi.nlm.nih.gov/pubmed/29874838
http://dx.doi.org/10.3390/ijms19061670