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Molecular Genetics of Frontotemporal Dementia Elucidated by Drosophila Models—Defects in Endosomal–Lysosomal Pathway

Frontotemporal dementia (FTD) is the second most common senile neurodegenerative disease. FTD is a heterogeneous disease that can be classified into several subtypes. A mutation in CHMP2B locus (CHMP2B(intron5)), which encodes a component of endosomal sorting complex required for transport-III (ESCR...

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Detalles Bibliográficos
Autores principales: Vandal, Sarah E., Zheng, Xiaoyue, Ahmad, S. Tariq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032313/
https://www.ncbi.nlm.nih.gov/pubmed/29890743
http://dx.doi.org/10.3390/ijms19061714