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Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway

Hepatic stellate cell (HSC) activation is responsible for hepatic fibrogenesis and is associated with an overexpression of transcription 3 (STAT3). Luteolin, a common dietary flavonoid with potent anti-inflammatory properties, has previously demonstrated antifibrogenic properties in HSCs but the mec...

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Detalles Bibliográficos
Autores principales: Cummins, Claire B., Wang, Xiaofu, Nunez Lopez, Omar, Graham, Gabriel, Tie, Hong-Yan, Zhou, Jia, Radhakrishnan, Ravi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032316/
https://www.ncbi.nlm.nih.gov/pubmed/29795016
http://dx.doi.org/10.3390/ijms19061567