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Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway
Hepatic stellate cell (HSC) activation is responsible for hepatic fibrogenesis and is associated with an overexpression of transcription 3 (STAT3). Luteolin, a common dietary flavonoid with potent anti-inflammatory properties, has previously demonstrated antifibrogenic properties in HSCs but the mec...
Autores principales: | Cummins, Claire B., Wang, Xiaofu, Nunez Lopez, Omar, Graham, Gabriel, Tie, Hong-Yan, Zhou, Jia, Radhakrishnan, Ravi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032316/ https://www.ncbi.nlm.nih.gov/pubmed/29795016 http://dx.doi.org/10.3390/ijms19061567 |
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