MK-0677, a Ghrelin Agonist, Alleviates Amyloid Beta-Related Pathology in 5XFAD Mice, an Animal Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive deficits, neuroinflammation, and neuronal death. The primary pathogenic cause is believed to be the accumulation of pathogenic amyloid beta (Aβ) assemblies in the brain. Ghrelin, which is a peptide hormon...

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Detalles Bibliográficos
Autores principales: Jeong, Yu-on, Shin, Soo Jung, Park, Jun Yong, Ku, Bo Kyeong, Song, Ji Soo, Kim, Jwa-Jin, Jeon, Seong Gak, Lee, Sang Min, Moon, Minho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032329/
https://www.ncbi.nlm.nih.gov/pubmed/29912176
http://dx.doi.org/10.3390/ijms19061800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032329/
https://www.ncbi.nlm.nih.gov/pubmed/29912176
http://dx.doi.org/10.3390/ijms19061800

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