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Ligand Access Channels in Cytochrome P450 Enzymes: A Review

Quantitative structure-activity relationships may bring invaluable information on structural elements of both enzymes and substrates that, together, govern substrate specificity. Buried active sites in cytochrome P450 enzymes are connected to the solvent by a network of channels exiting at the dista...

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Detalles Bibliográficos
Autores principales: Urban, Philippe, Lautier, Thomas, Pompon, Denis, Truan, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032366/
https://www.ncbi.nlm.nih.gov/pubmed/29848998
http://dx.doi.org/10.3390/ijms19061617