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Ligand Access Channels in Cytochrome P450 Enzymes: A Review
Quantitative structure-activity relationships may bring invaluable information on structural elements of both enzymes and substrates that, together, govern substrate specificity. Buried active sites in cytochrome P450 enzymes are connected to the solvent by a network of channels exiting at the dista...
Autores principales: | Urban, Philippe, Lautier, Thomas, Pompon, Denis, Truan, Gilles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032366/ https://www.ncbi.nlm.nih.gov/pubmed/29848998 http://dx.doi.org/10.3390/ijms19061617 |
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