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A peptide‐display protein scaffold to facilitate single molecule force studies of aggregation‐prone peptides
Protein aggregation is linked with the onset of several neurodegenerative disorders, including Parkinson's disease (PD), which is associated with the aggregation of α‐synuclein (αSyn). The structural mechanistic details of protein aggregation, including the nature of the earliest protein–protei...
Autores principales: | Doherty, Ciaran P. A., Young, Lydia M., Karamanos, Theodoros K., Smith, Hugh I., Jackson, Matthew P., Radford, Sheena E., Brockwell, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032367/ https://www.ncbi.nlm.nih.gov/pubmed/29417650 http://dx.doi.org/10.1002/pro.3386 |
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