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P2RX7 Purinoceptor as a Therapeutic Target—The Second Coming?
The P2RX7 receptor is a unique member of a family of extracellular ATP (eATP)-gated ion channels expressed in immune cells, where its activation triggers the inflammatory cascade. Therefore, P2RX7 has been long investigated as a target in the treatment of infectious and inflammatory diseases. Subseq...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032550/ https://www.ncbi.nlm.nih.gov/pubmed/30003075 http://dx.doi.org/10.3389/fchem.2018.00248 |