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PATIENT-DERIVED XENOGRAFTS AS A PRECLINICAL MODEL FOR BONE SARCOMAS

OBJECTIVE: The purpose of this study was to reproduce a mouse model of bone sarcomas for use in cancer research. METHODS: A fresh sample of the tumor tissue was implanted subcutaneously into nude mice. When the patient-derived xenograft (PDX) reached a volume of 1500 mm(3), it was harvested for re-i...

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Detalles Bibliográficos
Autores principales: MEOHAS, WALTER, GRANATO, REGINA ALCANTARA, GUIMARÃES, JOÃO ANTONIO MATHEUS, DIAS, RHAYRA BRAGA, FORTUNA-COSTA, ANNELIESE, DUARTE, MARIA EUGENIA LEITE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ATHA EDITORA 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032614/
https://www.ncbi.nlm.nih.gov/pubmed/29983625
http://dx.doi.org/10.1590/1413-785220182602186998