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PATIENT-DERIVED XENOGRAFTS AS A PRECLINICAL MODEL FOR BONE SARCOMAS
OBJECTIVE: The purpose of this study was to reproduce a mouse model of bone sarcomas for use in cancer research. METHODS: A fresh sample of the tumor tissue was implanted subcutaneously into nude mice. When the patient-derived xenograft (PDX) reached a volume of 1500 mm(3), it was harvested for re-i...
Autores principales: | MEOHAS, WALTER, GRANATO, REGINA ALCANTARA, GUIMARÃES, JOÃO ANTONIO MATHEUS, DIAS, RHAYRA BRAGA, FORTUNA-COSTA, ANNELIESE, DUARTE, MARIA EUGENIA LEITE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
ATHA EDITORA
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032614/ https://www.ncbi.nlm.nih.gov/pubmed/29983625 http://dx.doi.org/10.1590/1413-785220182602186998 |
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