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Mycophenolic Acid Synergizing with Lipopolysaccharide to Induce Interleukin-1β Release via Activation of Caspase-1

BACKGROUND: The previous study showed that mycophenolic acid (MPA) synergizing with lipopolysaccharide (LPS) promoted interleukin (IL)-1β release, but the mechanism is unclear. This study aimed to investigate the mechanism of MPA synergizing with LPS to induce IL-1β release. METHODS: Undiluted human...

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Detalles Bibliográficos
Autores principales: Huang, Xue-Chan, He, Yi, Zhuang, Jian, He, Juan, Luo, Gui-Hu, Han, Jiao-Chan, Sun, Er-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032679/
https://www.ncbi.nlm.nih.gov/pubmed/29941706
http://dx.doi.org/10.4103/0366-6999.235116