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T cell senescence and CAR-T cell exhaustion in hematological malignancies
T cell senescence has been recognized to play an immunosuppressive role in the aging population and cancer patients. Strategies dedicated to preventing or reversing replicative and premature T cell senescence are required to increase the lifespan of human beings and to reduce the morbidity from canc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032767/ https://www.ncbi.nlm.nih.gov/pubmed/29973238 http://dx.doi.org/10.1186/s13045-018-0629-x |