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A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency

Defects in the respiratory chain, interfering with energy production in the cell, are major underlying causes of mitochondrial diseases. In spite of this, the surprising variety of clinical symptoms, disparity between ages of onset, as well as the involvement of mitochondrial impairment in ageing an...

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Detalles Bibliográficos
Autores principales: Simard, Marie‐Lune, Mourier, Arnaud, Greaves, Laura C, Taylor, Robert W, Stewart, James B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032845/
https://www.ncbi.nlm.nih.gov/pubmed/29660116
http://dx.doi.org/10.1002/path.5084