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Isolation of a high‐affinity Bet v 1‐specific IgG‐derived ScFv from a subject vaccinated with hypoallergenic Bet v 1 fragments

BACKGROUND: Recombinant hypoallergenic allergen derivatives have been used in clinical immunotherapy studies, and clinical efficacy seems to be related to the induction of blocking IgG antibodies recognizing the wild‐type allergens. However, so far no treatment‐induced IgG antibodies have been chara...

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Detalles Bibliográficos
Autores principales: Gadermaier, E., Marth, K., Lupinek, C., Campana, R., Hofer, G., Blatt, K., Smiljkovic, D., Roder, U., Focke‐Tejkl, M., Vrtala, S., Keller, W., Valent, P., Valenta, R., Flicker, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032869/
https://www.ncbi.nlm.nih.gov/pubmed/29315611
http://dx.doi.org/10.1111/all.13394