Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin‐deficient mice and Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a fatal disorder caused by absence of functional dystrophin protein. Compensation in dystrophin‐deficient (mdx) mice may be achieved by overexpression of its fetal paralogue, utrophin. Strategies to increase utrophin levels by stimulating promoter activity using...

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Detalles Bibliográficos
Autores principales: Perkins, Kelly J., Davies, Kay E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032923/
https://www.ncbi.nlm.nih.gov/pubmed/29772070
http://dx.doi.org/10.1002/1873-3468.13099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032923/
https://www.ncbi.nlm.nih.gov/pubmed/29772070
http://dx.doi.org/10.1002/1873-3468.13099

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