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The tale of two talins – two isoforms to fine‐tune integrin signalling

Talins are cytoplasmic adapter proteins essential for integrin‐mediated cell adhesion to the extracellular matrix. Talins control the activation state of integrins, link integrins to cytoskeletal actin, recruit numerous signalling molecules that mediate integrin signalling and coordinate recruitment...

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Detalles Bibliográficos
Autores principales: Gough, Rosemarie E., Goult, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032930/
https://www.ncbi.nlm.nih.gov/pubmed/29723415
http://dx.doi.org/10.1002/1873-3468.13081