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Brief Report: A Randomized, Double‐Blind, Parallel‐Group, Placebo‐Controlled, Multiple‐Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis

OBJECTIVE: To evaluate the safety and potential efficacy of AMG 557, a fully human antibody directed against the inducible T cell costimulator ligand (ICOSL) in patients with systemic lupus erythematosus (SLE) with arthritis. METHODS: In this phase Ib, randomized, double‐blind, placebo‐controlled st...

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Detalles Bibliográficos
Autores principales: Cheng, Laurence E., Amoura, Zahir, Cheah, Benjamin, Hiepe, Falk, Sullivan, Barbara A., Zhou, Lei, Arnold, Gregory E., Tsuji, Wayne H., Merrill, Joan T., Chung, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032945/
https://www.ncbi.nlm.nih.gov/pubmed/29513931
http://dx.doi.org/10.1002/art.40479