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A Targeted LC‐MS Strategy for Low‐Abundant HLA Class‐I‐Presented Peptide Detection Identifies Novel Human Papillomavirus T‐Cell Epitopes

For rational design of therapeutic vaccines, detailed knowledge about target epitopes that are endogenously processed and truly presented on infected or transformed cells is essential. Many potential target epitopes (viral or mutation‐derived), are presented at low abundance. Therefore, direct detec...

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Detalles Bibliográficos
Autores principales: Blatnik, Renata, Mohan, Nitya, Bonsack, Maria, Falkenby, Lasse G., Hoppe, Stephanie, Josef, Kathrin, Steinbach, Alina, Becker, Sara, Nadler, Wiebke M., Rucevic, Marijana, Larsen, Martin R., Salek, Mogjiborahman, Riemer, Angelika B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033010/
https://www.ncbi.nlm.nih.gov/pubmed/29603667
http://dx.doi.org/10.1002/pmic.201700390