Loss of N‐WASP drives early progression in an Apc model of intestinal tumourigenesis

N‐WASP (WASL) is a widely expressed cytoskeletal signalling and scaffold protein also implicated in regulation of Wnt signalling and homeostatic maintenance of skin epithelial architecture. N‐WASP mediates invasion of cancer cells in vitro and its depletion reduces invasion and metastatic disseminat...

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Detalles Bibliográficos
Autores principales: Morris, Hayley T, Fort, Loic, Spence, Heather J, Patel, Rachana, Vincent, David F, Park, James H, Snapper, Scott B, Carey, Francis A, Sansom, Owen J, Machesky, Laura M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033012/
https://www.ncbi.nlm.nih.gov/pubmed/29672847
http://dx.doi.org/10.1002/path.5086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033012/
https://www.ncbi.nlm.nih.gov/pubmed/29672847
http://dx.doi.org/10.1002/path.5086

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