Cargando…

SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury

Patients with anterior cruciate ligament (ACL) rupture are two times as likely to develop posttraumatic osteoarthritis (PTOA). Annually, there are ∼900,000 knee injuries in the United States, which account for ∼12% of all osteoarthritis (OA) cases. PTOA leads to reduced physical activity, deconditio...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Jiun C, Christiansen, Blaine A, Murugesh, Deepa K, Sebastian, Aimy, Hum, Nicholas R, Collette, Nicole M, Hatsell, Sarah, Economides, Aris N, Blanchette, Craig D, Loots, Gabriela G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033030/
https://www.ncbi.nlm.nih.gov/pubmed/29377313
http://dx.doi.org/10.1002/jbmr.3397