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Pharmacokinetics of metformin in patients with gastrointestinal intolerance

AIMS: To assess potential causes of metformin intolerance, including altered metformin uptake from the intestine, increased anaerobic glucose utilization and subsequent lactate production, altered serotonin uptake, and altered bile acid pool. METHODS: For this pharmacokinetic study, we recruited 10...

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Detalles Bibliográficos
Autores principales: McCreight, Laura J., Stage, Tore B., Connelly, Paul, Lonergan, Mike, Nielsen, Flemming, Prehn, Cornelia, Adamski, Jerzy, Brøsen, Kim, Pearson, Ewan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033038/
https://www.ncbi.nlm.nih.gov/pubmed/29457876
http://dx.doi.org/10.1111/dom.13264