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NAD(P)H‐Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application

Asymmetric reductive aminations are some of the most important reactions in the preparation of active pharmaceuticals, as chiral amines feature in many of the world's most important drugs. Although many enzymes have been applied to the synthesis of chiral amines, the development of reductive am...

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Detalles Bibliográficos
Autores principales: Sharma, Mahima, Mangas‐Sanchez, Juan, Turner, Nicholas J., Grogan, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033044/
https://www.ncbi.nlm.nih.gov/pubmed/30008635
http://dx.doi.org/10.1002/adsc.201700356